People at risk of cardiovascular disease are advised to reduce their cholesterol levels, usually by taking statins. Statins work by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol.
A recent study, found that people with naturally lower levels of low-density lipoprotein (LDL) cholesterol were less likely to develop heart disease however were more vulnerable to developing type II diabetes and scientists believe reducing LDL levels by taking statins may have the same effect.
It is generally considered that there is an increased risk of approximately 10% of developing type II diabetes in patients prescribed statins. However Cederberg et al (2015) have recently quoted an increased risk of 46% of developing type II diabetes in patients prescribed statins (simvastatin, atorvastatin).
Supplementation with Coenzyme Q10 (CoQ10) may be of benefit to those taking statin medications. CoQ10 is a vitamin-like substance which is required by the body for the normal functioning of all tissues and those with the highest energy requirements (heart and muscles) are particularly reliant on an adequate supply. The body’s synthesis of CoQ10 is depleted by ageing, illness and by certain medications including statins. Supplementation with CoQ10 can prevent the depletion of CoQ10 levels which is associated with statins.
CoQ10 supplementation may be beneficial to statin users because:
Experts have recommended patients still continue to use statins, with the benefits in heart attack prevention outweighing the side effects. CoQ10 does not interfere with the cholesterol lowering work of statins.September 2016